1057. CpG-adjuvanted Hepatitis B vaccination improves seroprotection rates in Veterans with HIV
نویسندگان
چکیده
منابع مشابه
CPG 7909 adjuvant plus hepatitis B virus vaccination in HIV-infected adults achieves long-term seroprotection for up to 5 years.
BACKGROUND Human immunodeficiency virus (HIV)-infected persons are hyporesponsive to hepatitis B virus (HBV) vaccination. CPG 7909 is an oligodeoxynucleotide containing immunostimulatory CpG motifs that activate human B and plasmacytoid dendritic cells via Toll-like receptor 9. We previously reported that addition of CPG 7909 to a commercial HBV vaccine enhanced the kinetics, magnitude, and lon...
متن کاملImmune Response to Standard Hepatitis B Vaccination in HIV-Infected Patients
Background: Due to their similar routes of transmission, human immunodeficiency virus (HIV) and hepatitis B virus (HBV) co-infection occurs considerably. HBV infection progresses more rapidly in HIV-infected patients. Therefore, HBV vaccination of all non-immune HIV infected patients is recommended. On the other hand, HIV-infected subjects have suboptimal responses to HBV vaccine. In this study...
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BACKGROUND The impact of hepatitis B virus (HBV) vaccination campaigns on HBV epidemiology needs to be evaluated, in order to assess the long-term immunity offered by vaccines against HBV. OBJECTIVES To evaluate the current status of anti-HBV vaccine coverage among healthcare workers (HCWs) in Southern Italy, and to determine the long-term persistence of antibodies to hepatitis B surface anti...
متن کاملSeroprotection after recombinant hepatitis B vaccination among newborn infants: a review.
INTRODUCTION Hepatitis B vaccination starting at birth provides a safety net for infants exposed to hepatitis B virus (HBV) during delivery or in early life. Hepatitis B vaccine is recommended in the United States for infants prior to birthing facility discharge, and within the first 12h of life for infants born to hepatitis B surface antigen (HBsAg)-positive mothers. We performed a literature ...
متن کاملseroconversion rates after hepatitis-b vaccination in children
background: hepatitis- b infection is one of the infectious diseases that transmits via blood transfiosion, blood product, injection, mother to fetus and sexual contact. protective anti hepatitis-b titer are observed in more than 90% of healthy children. the aim of this study was to evaluate seroconversion rates in children who received routine vaccination program. methods: a cross sectional st...
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ژورنال
عنوان ژورنال: Open Forum Infectious Diseases
سال: 2020
ISSN: 2328-8957
DOI: 10.1093/ofid/ofaa439.1243